Grey’s Anatomy, a cornerstone of TV drama, has been breaking hearts for almost two decades with its gripping storylines and unforgettable character exits. From tragic deaths to unexpected departures, let’s delve into the most heart-wrenching goodbyes that left fans reaching for tissues.
12. Dr. George O’Malley (T.R. Knight)
In a shocking twist, George’s exit in Season 5 remains one of the most devastating.
His heroic act of saving a woman from an oncoming bus only to be fatally injured himself was both a gut-punch and a masterclass in tragic storytelling. His unrecognizable state until the poignant reveal as "007" added layers to the heartbreak.
11. Dr. Lexie Grey (Chyler Leigh)
Crushed under the wreckage of a plane crash in Season 8, Lexie’s death was graphic and emotionally charged. Her final moments with Mark Sloan, confessing their love for each other, were gut-wrenching, leaving fans devastated as Meredith's sister met an untimely end.
10. Dr. Mark Sloan (Eric Dane)
Following the same plane crash that claimed Lexie, Mark’s death in Season 9 was equally tragic. Surviving the crash only to succumb to his injuries later, Mark’s final scenes were a poignant farewell to a character beloved for his humor and depth.
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