As prepares to kick off its 21st season, there’s no shortage of buzz around the show’s return. The medical drama that has been a television staple for over two decades is set to continue its legacy with a mix of familiar faces and new surprises that fans won’t want to miss.
The official premiere date for the 21st season has been announced, and fans should mark their calendars for Thursday, September 26, 2024, at 10 PM ET.
This later time slot is a strategic shift to make room for ABC's new medical drama , ensuring Thursday nights remain full of intense hospital drama.

Some of the most beloved characters are confirmed to return this season. Ellen Pompeo is back as Meredith Grey, set to appear in at least seven episodes. Joining her are fan favorites Chandra Wilson (Miranda Bailey), James Pickens Jr.
(Richard Webber), Kevin McKidd (Owen Hunt), Kim Raver (Teddy Altman), and Camilla Luddington (Jo Wilson), ensuring the show retains its emotional core.
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