Jo Understands Alex Completely
Jo Wilson truly understands Alex Karev. She knows where he comes from and why he is the way he is, loving him unconditionally despite his flaws. This deep understanding allows them to have a strong, resilient relationship, as Jo is always there for Alex, even during tough times.
Izzie's Disappearing Act
In contrast, Izzie Stevens left Alex heartbroken when she disappeared after being fired from the hospital.
Despite Alex’s unwavering support during her illness, Izzie chose to leave him without explanation, showing a lack of commitment that hurt Alex deeply.
Jo’s Unwavering Loyalty
Jo has always been loyal to Alex. Even when others showed interest in her, Jo remained committed to their relationship, preferring to work through their issues rather than give up. This loyalty proves how much she values their bond.
Izzie’s Love for Denny
Izzie’s intense love for patient Denny Duquette highlighted a significant issue in her relationship with Alex.
Her willingness to go to unethical lengths for Denny suggested that her passion lay elsewhere, even when Alex was in her life.
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